Jennifer Trowbridge – Principal Investigator
Jen received her BSc in Genetics and PhD in Microbiology & Immunology from The University of Western Ontario. Her postdoctoral training was with Stuart H. Orkin at the Dana-Farber Cancer Institute. Jen has received the Janet Rowley Award from the International Society for Experimental Hematology (ISEH), an American Society of Hematology (ASH) Scholar Award, the V Scholar Award and the Ellison Medical Foundation New Scholar in Aging Award. She is an Associate Professor at The Jackson Laboratory and at Tufts University School of Medicine. Email: Jennifer.Trowbridge@jax.org
Kira Young – Associate Research Scientist
Kira received her BS in Chemical Engineering and PhD in Functional Genomics from the University of Maine, and completed her postdoctoral training in the Trowbridge lab. Kira’s project focuses on understanding causative changes driving hematopoietic aging, particularly in terms of alterations in the hematopoietic cell-extrinsic bone marrow microenvironment. Kira was the recipient of fellowship funding through a JAX T32 training grant, a JAX Pyewacket fellowship award and the American Society of Hematology (ASH) Scholar award. Email: Kira.Young@jax.org
Jennifer Myers SanMiguel – Postdoctoral Fellow
Jen received her BA in Biology from Colby College and PhD in Cell and Molecular Biology from the University of Pennsylvania. Jen conducted her thesis work in the laboratory of Dr. Marisa Bartolomei studying the epigenetic regulator TET1 and its role during developmental epigenetic reprogramming. Jen’s project focuses on understanding how inflammation in the context of aging contributes to clonal hematopoiesis via mutant HSC selection. Jen is a current recipient of an ASH Scholar Award. Email: Jennifer.SanMiguel@jax.org
Jayna Mistry – Postdoctoral Fellow
Jayna received her BSc (Hons) from Aston University and her PhD from the University of East Anglia and Earlham Institute in the UK. She conducted her thesis work in the laboratory of Dr. Stuart Rushworth studying the role of metabolism in stress hematopoiesis. Jayna’s focus is on understanding aging-associated mechanisms of Dnmt3a-mutant clonal hematopoiesis. Jayna is a current recipient of a JAX Scholar Award. Email: Jayna.Mistry@jax.org
Logan Schwartz – Ph.D. candidate
Logan received her BS in Molecular Genetics from The University of Rochester and subsequently was a research technician with Drs. Christopher Ott and Jay Bradner at Massachusetts General Hospital and the Dana-Farber Cancer Institute. Logan is currently a PhD candidate in the Tufts Graduate School of Biomedical Sciences Genetics Program. Logan’s project focuses on understanding how changes in the bone marrow microenvironment synergize with somatic mutations in HSCs to promote clonal hematopoiesis. Logan is the recipient of a Burroughs Wellcome Fund training fellowship from JAX and NIH F31 fellowship grant from the NIDDK. Email: Logan.Schwartz@jax.org
Kristina Mujica – Research Lab Associate Manager
Tina received her BS in Wildlife Biology from Unity College and Masters degree from Johns Hopkins University. Prior to joining the lab, Tina had previous experience as an animal care technician here at JAX, and as a veterinary technician at an animal shelter. Tina serves as our laboratory manager for day-to-day operations, coordinates our animal colony, trains incoming lab members, and supports experiments across the laboratory. Email: Kristina.Mujica@jax.org
Patricia Colom Díaz – Postbacc Fellow
Patricia received her Bachelor of Science in Biology from the University of Puerto Rico. She joined the postbacc program having had laboratory experience in genetics research and STEM mentoring experience with high school students. Patricia’s project focuses on drug sensitivity and resistance mechanisms in clonal hematopoeisis and leukemia. Patricia aspires to pursue an MD or MD-PhD degree following completion of her postbacc position. Email: Patricia.Colom@jax.org
Griffin Nye – Research Assistant II
Griffin received his Bachelor of Science in Biomedical Science from the University of New Hampshire with experience in microbial research. Griffin supports experiments across the laboratory in the areas of clonal hematopoiesis, inflammation and metabolic regulation. Email: Griffin.Nye@jax.org
Brandon James – Research Assistant I
Brandon received his Bachelor of Science in Biology from Delaware Valley University, where he was selected into the DelVel Honors Program and ALD Honors Society. Brandon supports experiments across the laboratory, particularly focused on a project to discover of methylation-independent functions of mutant Dnmt3a in driving clonal hematopoiesis. Brandon aspires to return to school to pursue an MD-PhD program. Email: Brandon.James@jax.org
Matthew Bauer – Research Assistant II
Matt received his Bachelor of Science in Biochemistry from Illinois State University. He joined our lab after 5 years as a laboratory manager and technician at The University of Chicago. Matt supports experiments across the laboratory and strives to be at the bench and actively participate in new scientific discoveries. Email: Matthew.Bauer@jax.org
Former Lab Members
PhD Program:
- Eraj Khokhar, PhD, current: postdoctoral fellow, UMass Medical School
- Sneha Borikar, PhD, current: Principal Scientist I, Novartis
JAX Summer Student Program:
- Brandon James, current: The Jackson Laboratory
- Maximo Kesselhaut, current; undergraduate, Yale
- Teniola Idowu, current: PhD candidate, NYU
- Zollie Yavarow, current: PhD/MA candidate, Duke University
- Matthew Loberg, current: MD/PhD candidate, Vanderbilt
- Jennifer Ditano Hines, PhD current: Senior Scientist I, AbbVie
High School Interns:
- Olivia Erickson
Research Assistants:
- Abimbola Lawal
- Liz Eudy
- Amy LoTemplio
- Nicole Dean
- Matthew Loberg
- Becca Bell
- Tara Murphy
- Kaiden Waldron-Francis
- Charles Kanozak
The Trowbridge Lab 